OAKLAND, Calif. -- A's lefty Sean Manaea pitched the first no-hitter against Boston in 25 years, with an overturned call preserving the gem Saturday night in Oakland's 3-0 win over the sizzling Red Sox.

Manaea struck out 10, walked two and threw 108 pitches to finish off Oakland's first no-no since Dallas Braden tossed a perfect game against Tampa Bay in 2010.

Manaea got Hanley Ramirez to ground out to complete the first no-hitter versus the Red Sox since Seattle's Chris Bosio did it in 1993.

Boston looked as if it had a hit with two outs in the sixth at the Oakland Coliseum. Andrew Benintendi hit a grounder to the right side, slid around first baseman Matt Olson and was ruled safe.

After the umpires conferred, Benintendi was ruled out for going wide of the baseline.

Sandy Leon reached in the Red Sox fifth when A's shortstop Marcus Semien dropped a popup. The play was scored as an error.

Manaea (3-2) had been battered by Boston in three previous starts. But the 26-year-old cooled off a hard-hitting Red Sox team that had won eight in a row and 17 of 18.

BRAVES 4, METS 3

ATLANTA (AP) -- Johan Camargo tripled home the tying run, then scored on Ender Inciarte's bunt single as the Atlanta Braves scored twice in the ninth inning off Mets closer Jeurys Familia to beat New York 4-3 on Saturday night.

A crowd of 41,396 that was the largest of the season at SunTrust Stadium saw starters Jacob deGrom and Julio Teheran each pitch seven scoreless innings. After they left, the bullpens wilted.

Familia issued a leadoff walk to Dansby Swanson and Camargo followed with a triple that made it 3-all. With one out and runners at the corners, Inciarte put down a bunt to the right side. First baseman Adrian Gonzalez made a quick throw home, but Camargo was already across the plate with a headfirst dive.

Familia (1-1) entered the game unscored upon and tied for the major league lead with eight saves.

Jesse Biddle (1-0) went one inning for the win.

ASTROS 10, WHITE SOX 1

CHICAGO (AP) -- Josh Reddick hit a grand slam and a solo homer, and Houston pounded reeling Chicago.

Already struggling on the field -- and especially on the mound -- the White Sox were dealt another blow Saturday when they learned that reliever Danny Farquhar suffered a brain hemorrhage while collapsing in the dugout Friday night.

Dallas Keuchel, the 2015 AL Cy Young Award winner, cruised to his first victory after being staked to a big lead early. Keuchel (1-3) allowed one run and four hits in six innings while striking out six.

Marwin Gonzalez drove in two runs with a double, and Jose Altuve, Carlos Correa and Yuli Gurriel each had an RBI as Houston routed Chicago for a second straight night. Six of the seven Astros batters walked by White Sox starter Lucas Giolito (0-3) scored. Houston has won five straight.

BREWERS 6, MARLINS 5

MILWAUKEE (AP) -- Jesus Aguilar homered on the 13th pitch leading off the bottom of the ninth inning, and Milwaukee rallied for its fifth consecutive win.

Aguilar, who entered the game as a late-inning replacement, hit his first home run of the season off Junichi Tazawa (0-1).

Milwaukee tied the score in the eighth when Miami left fielder Derek Dietrich misplayed Eric Sogard's two-out popup to left, allowing Travis Shaw to score from second.

Jeremy Jeffress (2-0) pitched a scoreless inning of relief to get the win.

The Marlins have lost six of seven.

INDIANS 4, ORIOLES 0

BALTIMORE (AP) -- Mike Clevinger pitched a two-hitter in his first career complete game, and Cleveland hit three solo homers off Chris Tillman in a 4-0 victory.

Jose Ramirez went 3 for 4 with his team-leading fifth home run. Yan Gomes and Yonder Alonso also went deep for Cleveland, which came into the game ranked second-to-last in the AL in runs and last in batting average.

Clevinger (2-0) hardly needed the offensive support. Pitching on seven days' rest, the right-hander struck out three, walked two and allowed only one runner past first base.

It was Clevinger's 35th career start. His previous longest outing was 7 1/3 innings, earlier this month against Kansas City.

Tillman (0-4) gave up four runs, eight hits and a walk in six innings.

YANKEES 9, BLUE JAYS 1

NEW YORK (AP) -- Aaron Judge hit an early homer off respected Twitter rival Marcus Stroman, then scored on a disputed play during a seven-run burst in the sixth inning that sent New York over Toronto.

Judge put the Yankees up 2-0 with his sixth homer, a two-run drive in the third. It came after Stroman and Judge exchanged tweets at the end of last season during which the Toronto ace said their "future battles will be legendary."

Judge is now 7 for 16 with four home runs against Stroman (0-2).

Jordan Montgomery (2-0) pitched six innings and allowed one run on four hits.

DIAMONDBACKS 6, PADRES 2

PHOENIX (AP) -- Zack Godley settled down after a shaky start to throw 5 1/3 solid innings and singled home a run as Arizona beat San Diego.

A.J. Pollock had a solo homer and RBI single for Arizona. Deven Marrero tripled in a run, doubled and scored twice, and Paul Goldschmidt had a double and an RBI triple.

The NL West-leading Diamondbacks, losers to the Padres 4-1 on Friday night, will send left-hander Patrick Corbin to the mound Sunday to try to extend their franchise record with a seventh consecutive series win to start the season.

Pitching on his 28th birthday, Godley (3-1) gave up two runs in the first inning and blanked the Padres over the next 4 1/3. Andrew Chafin, Fernando Salas and T.J. McFarland held San Diego scoreless the rest of the way.

Clayton Richard (0-1) allowed three runs on five hits in five-plus innings.

CARDINALS 4, REDS 3

ST. LOUIS (AP) -- Yadier Molina hit a tiebreaking home run in the seventh inning and rookie reliever Jordan Hicks got Scooter Gennett to ground into a game-ending double play with the bases loaded, lifting St. Louis over Cincinnati.

The Cardinals have won seven of eight, including six against the Reds. The Reds dropped their fourth straight, and second under interim manager Jim Riggleman, and fell to 3-17 this season.

St. Louis has won 10 in a row from the Reds dating to last season, matching its longest streak against them since 1949, when the Cardinals won 11 straight.

Hicks (1-0) recorded the final seven outs. Jared Hughes (0-2) gave up Molina's sixth homer, a solo drive.

PHILLIES 6, PIRATES 2

PHILADELPHIA (AP) -- Rhys Hoskins hit a go-ahead three-run homer, Aaron Nola tossed seven impressive innings and Philadelphia beat Pittsburgh.

Nola (2-1) allowed two runs, six hits and struck out nine to help the Phillies win their third straight game and improve to 8-1 at home.

The Pirates have lost five of six after an 11-4 start.

Pittsburgh's Steven Brault gave up two runs and two hits in 5 1/3 innings. The lefty took a shutout into the sixth before things unraveled.

Brault hit Carlos Santana with a pitch and Odubel Herrera followed with a single. Michael Feliz (0-1) entered to face Hoskins, who drove a 1-2 pitch into the left-field seats for a 3-2 lead.

Hector Neris got the last four outs for his fourth save.

ROCKIES 5, CUBS 2

DENVER (AP) -- Nolan Arenado had two hits to back six strong innings from Tyler Anderson and Colorado used a big fifth inning to beat Chicago.

Anderson (1-0) got his first win in five starts and tamed a Chicago lineup that had 16 runs on 18 hits in the series opener on Friday night. The Cubs managed just six hits on the night, two from Albert Almora Jr., who had four in Friday's win.

Wade Davis pitched the ninth for his ninth save in 10 chances.

Chicago's offence wasn't as potent behind starter Yu Darvish (0-2). He started strong but left with two outs in the fifth after allowing five runs on five hits and walking four.

RAYS 10, TWINS 1

ST. PETERSBURG, Fla. (AP) -- C.J. Cron hit a pair of two-run homers and Blake Snell won his third straight start for Tampa Bay.

Cron's homer in the third inning put the Rays up 2-1 after Adeiny Hechavarria singled for their first hit off Kyle Gibson (1-1). Cron connected again in the seventh off Gabriel Moya, capping a five-run inning. It was his fourth homer of the season.

Joey Wendle had three hits and scored twice for the Rays, who won their third straight for the first time this year.

Snell (3-1) surrendered just one run for his third consecutive start, striking out six and allowing five hits in seven innings.

TIGERS 12, ROYALS 4

DETROIT (AP) -- Nicholas Castellanos homered and drove in three runs, and Detroit routed Kansas City.

The Tigers have won five of six. Detroit broke a 3-all tie with three runs in the fifth on a day when both starting pitchers were in almost constant trouble.

Mike Fiers (2-1) allowed two earned runs and 10 hits in 5 1/3 innings for the Tigers, and Royals starter Danny Duffy (0-3) yielded six runs and 10 hits in 4 2/3 innings.

Warwick Saupold pitched 2 1/3 perfect innings for his first career save.

Abraham Almonte had three hits for Kansas City, which has lost 10 of 11.

ANGELS 4, GIANTS 3

ANAHEIM, Calif. (AP) -- Albert Pujols drove a go-ahead, two-run home run into the seats in right-centre for career hit No. 2,992, and Mike Trout and Jefry Marte also went deep as Los Angeles snapped an ugly four-game losing streak.

Pujols, 38, hit a no-doubt, opposite-field shot to right-centre on an 0-1 pitch from lefty Derek Holland (0-3) with one out in the sixth. He needs eight hits to become the 32nd member of the 3,000-hit club. He went 1 for 4 as the designated hitter.

Pujols came up with runners on the corners and one out in the eighth and grounded into a double play.

Garrett Richards (3-0) struck out 11 in six innings and held San Francisco to two runs and five hits, with one walk.

The Angels lost 8-1 to the Giants on Friday night after being outscored 27-3 in a three-game sweep by the Boston Red Sox.

Keynan Middleton got a four-out save, his fifth.

DODGERS 4, NATIONALS 0

LOS ANGELES (AP) -- Joc Pederson, Kike Hernandez and Cody Bellinger all homered, and Hyun-Jin Ryu pitched seven innings of two-hit ball to lead Los Angeles.

Ryu (3-0) struck out eight and walked two, Tony Cingrani pitched the eighth and Kenley Jansen got the last three outs to finish the shutout and give the Dodgers their fifth win in the last six games.

Pederson hit a 96mph fastball on a 1-0 count from Washington starter Stephen Strasburg (2-2) six rows into the bleachers in centre field for his first home run of the season, staking the Dodgers to a 1-0 lead with one out in the second inning.

Hernandez made it 2-0 with two outs in the seventh, and Bellinger hit a towering two-run shot deep into the right-field bleachers in the eighth.

MARINERS 9, RANGERS 7

ARLINGTON, Texas (AP) -- Nelson Cruz homered for the 100th time at his former home, Robinson Cano hit a tiebreaking shot and Seattle held on to beat Texas.

Cano's two-run homer in the seventh made it 8-6 and capped a four-run outburst against reliever Alex Claudio (0-1), who gave up hits to all four batters he faced. Mitch Haniger also went deep later in the inning against Chris Martin.

Cruz hit a two-run home estimated at 453 feet in the fourth, which came one pitch after another towering drive down the left-field line was ruled foul -- and stayed that way after an umpire replay review. Of his 100 homers at the Rangers ballpark, 92 came when Cruz played for Texas from 2006-13.

Seattle's comeback spoiled 44-year-old Bartolo Colon's bid for his first win with the Rangers, and 21st in his career against the Mariners. Colon, who covered first base for the first two outs in the fifth, exited after 5 2/3 innings with a 5-4 lead.

Chasen Bradford (2-0) pitched two innings in relief of Seattle starter James Paxton. Edwin Diaz got the final four outs for his AL-leading eighth save.