Paxlovid key in COVID-19 fight, but easy access is important: doctors
A pill to treat COVID-19 appears to be the country's best hope, outside of vaccines and strong public health measures, to keep hospitals from being overrun with cases of the virus now and in the future, doctors say.
But with infections surging across the country, experts say the patchwork distribution system for Paxlovid in various parts of Canada may inhibit those who most need the drug from getting it in time.
Paxlovid, an antiviral, has shown a 90 per cent reduction in hospitalizations among unvaccinated patients with the Delta variant who received the drug within five days of symptom onset.
Those who might need the drug the most would do well to learn ahead of time how they might access it, the country's chief public health officer said this week.
"My message to all Canadians who may be at high risk, such as the immunocompromised: figure out in your community, right now, how you can get access to that medication should you need it because it is a bit different across different areas of Canada," Dr. Theresa Tam said on Tuesday.
The federal government has distributed about 150,000 courses of Paxlovid to the provinces and territories, Tam said. Most of the provinces have a centralized distribution system for the drug, often through hospitals and assessment centres, and eligibility varies across the country.
"I think all of us would like to see Paxlovid being mobilized more widely," Tam said, adding that Health Canada is working with various jurisdictions on the issue.
"We will be using these kinds of medications in a more significant way as we have more access to antivirals in the future, which is great news. We just need to know how to get it out to people fast."
Quebec's pharmacists can prescribe Paxlovid, although those who are at the highest risk for severe disease are the only ones who can get it.
Ontario had a centralized distribution system, largely through hospitals and assessment centres, until the province announced Monday it would allow select pharmacies to distribute the drug to those who have a prescription.
The move was applauded by infectious disease experts.
"It's a good move because it makes it a lot easier for people who are eligible and are prescribed packs," said Dr. Gerald Evans, an infectious disease professor at Queen's University and the medical director of infection prevention and control at Kingston Health Sciences Centre.
At Evans' hospital, doctors only had two ways of getting patients the drug: getting them to drive to the hospital or couriering it to them, even if they live an hour's drive from Kingston, Ont.
"The drug is inaccessible for many patients," he said.
He cautioned that Paxlovid, which must be started within the first five days of symptoms, does not work for everybody and said the best protection remains vaccination against COVID-19.
Other provinces should follow Quebec and Ontario's lead, said Dr. Zain Chagla, an associate professor of infectious disease with McMaster University in Hamilton.
"The drug needs to be decentralized," Chagla said.
Ontario this week also expanded eligibility parameters for Paxlovid to anyone 70 and older, people 60 and older with fewer than three doses of a COVID-19 vaccine, and people 18 and older with fewer than three vaccine doses and at least one risk factor such as a chronic medical condition.
"We have a drug that can significantly mitigate hospitalization," Chagla said. "We need the community to now start being prescribers and providers to make sure that their patients aren't hospitalized."
In Ontario, hospitalizations and intensive care unit capacities have been the key drivers for the imposition and lifting of public health measures in past COVID-19 waves. The provincial government lifted nearly all public health measures, including masking in most public spaces, in mid-March.
Ontario is now in its sixth wave – driven by the lifting of those public health measures, according to Public Health Ontario – and hospitalizations are rising.
Chagla said he has prescribed Paxlovid to about 150 people over the last month and cautioned that it interacts with many medications, including blood thinners, cholesterol medications, birth control and seizure medications.
"About 95 per cent of these potential interactions can be dealt with in just a few minutes of my time," he said. "It's not insurmountable by any means. The vast majority of people can hold their medications or deal with medication changes for a week to get on this."
In Quebec, those who are deemed "high risk" for complications from COVID-19 and meet certain criteria are eligible for Paxlovid, although some doctors believe the criteria are too strict.
"It really comes down to how is high risk defined," said Dr. Emily McDonald, an associate professor of medicine at the McGill University Health Centre. "I or someone else might define high risk differently than how the government has defined it."
But McDonald said that is a trade-off to be able to give the pharmacists the ability to prescribe Paxlovid.
Each province has different eligibility criteria and that, when coupled with a paucity of communications about the drug, leaves the public in the dark, McDonald said.
"It's a matter of access and communication and we have to address both," she said. "A simpler message is more likely to be successful."
-With files from Laura Osman in Ottawa.
This report by The Canadian Press was first published April 13, 2022.
___
Get in touch
Have you had COVID-19 more than once in recent months? We want to hear from you. Email dotcom@bellmedia.ca.
Please include your name, location, and contact information if you are willing to speak to a journalist with CTV News.
Your comments may be used in a CTVNews.ca story.
CTVNews.ca Top Stories
Trudeau talks border, trade in surprise dinner with Trump at Mar-a-Lago
Prime Minister Justin Trudeau discussed border security and trade during a surprise dinner with U.S.-president elect Donald Trump at Mar-a-Lago in West Palm Beach, Fla. on Friday evening, according to senior government sources.
W5 Investigates 'I never took part in beheadings': Canadian ISIS sniper has warning about future of terror group
An admitted Canadian ISIS sniper held in one of northeast Syria’s highest-security prisons has issued a stark warning about the potential resurgence of the terror group.
Poilievre suggests Trudeau is too weak to engage with Trump, Ford won't go there
While federal Conservative Leader Pierre Poilievre has taken aim at Prime Minister Justin Trudeau this week, calling him too 'weak' to engage with U.S. president-elect Donald Trump, Ontario Premier Doug Ford declined to echo the characterization in an exclusive Canadian broadcast interview set to air this Sunday on CTV's Question Period.
Montreal researchers make breakthrough discovery in fighting HIV
Researchers in Montreal have made a breakthrough discovery in HIV research by finding a way to expel the virus from its hiding places and destroy it.
Man who died trying to help stranded motorist identified as Khalid Farooq, father of 5
The man who lost his life trying to help a stranded motorist Wednesday has been identified as Khalid Farooq.
Are scented candles bad for you? What the science says
Concerns about the safety of candles are rooted in the chemical reactions that occur when you burn them, as well as in the artificial fragrances and colorants that contribute to the various scents you may love.
Man wanted after allegedly hitting vehicle repeatedly with hatchet near Toronto courthouse
Police are searching for a man who allegedly hit a car with a hatchet multiple times while yelling at the driver near a courthouse in downtown Toronto earlier this week.
'Very alarming:' Online scams spike during the holidays
Shoppers are out looking for the best deals on gifts for their loved ones. However, the RCMP and the Better Business Bureau are warning people that the deals they’re seeing online might be too good to be true.
Trump and Republicans in Congress eye an ambitious 100-day agenda, starting with tax cuts
Republicans are planning an ambitious 100-day agenda with U.S. president-elect Donald Trump in the White House and GOP lawmakers in a congressional majority to accomplish their policy goals.
Local Spotlight
Regina's LED volume wall leaving Sask. months after opening
Less than a year after an LED volume wall was introduced to the film world in Saskatchewan, the equipment is making its exit from the province.
'My dear Carmel': Lost letters returned to 103-year-old Guelph, Ont. woman
A young history buff was able to reunite a Guelph, Ont. woman with letters written by her husband almost 80 years ago.
'We have to do something': Homeless advocates in Moncton reaching out for help over holidays
Twice a week, Joanne and Jeff Jonah fill up their vehicle full of snacks and sandwiches and deliver them to the homeless in downtown Moncton, N.B.
100-year-old Winnipeg man walks blocks to see his wife
It's considered lucky to live to be 100, but often when you hit that milestone, you're faced with significant mobility issues. Not Winnipeg's Jack Mudry. The centenarian regularly walks five blocks to get where he wants to go, the care home where his wife Stella lives.
Video shows B.C. cat bursting through pet door to confront raccoons
Several hungry raccoons were chased off a B.C. couple’s deck this week by one over-confident house cat – who was ultimately lucky to saunter away unscathed.
Trailer Park Boys host Canadian premiere of new movie in Dartmouth
Sunday night was a big night for the Trailer Park Boys, as Ricky, Julian and Bubbles hosted an advanced screening of their new movie in Dartmouth, N.S.
Deer spotted wearing high-visibility safety jacket in Northern B.C.
Andrea Arnold is used to having to slow down to let deer cross the road in her Northern B.C. community. But this weekend she saw something that made her pull over and snap a photo.
From cellphones to dentures: Inside Halifax Transit’s lost and found
Every single item misplaced on a bus or ferry in the Halifax Regional Municipality ends up in a small office at the Halifax Transit Bridge Terminal in Dartmouth, N.S.
Torontonians identify priorities, concerns in new city survey
A new public opinion survey has found that 40 per cent of Torontonians don’t feel safe, while half reported that the quality of life in the city has worsened over the last year.